Method of production of drugs: Table., Film-coated, to 80 mg. Indications for use slaker benign prostatic hyperplasia in order to reduce the size of the prostate gland and therefore reduce the symptoms of dysuria. Contraindications to the use of drugs: hypersensitivity to any inhredientiv, members of the drug, pregnancy, lactation, infancy. Side effects and complications in the use of drugs: postural hypotension after the first dose or first few doses, dizziness, asthenia, nasal congestion, peripheral edema, drowsiness, nausea, increased heartbeat, blurred vision, headache, dyspnea, myalgia, arthralgia, AR dysuria; patients with hypovolemia and sodium deficiency may be more sensitive to the orthostatic effect of terazosin, slaker effect may be more pronounced for physical activities. Method of production of drugs: Table., Coated tablets, 5 mg. Method of production of drugs: Table., Coated tablets, cap. slaker for use drugs: Cytosine Diphosphate incontinence, urgency to West syndrome and polakiuriya (intensive urination) in cases of unstable bladder function neurogenic origin or due to idiopathic detrusor instability features, night enuresis in children (aged 5 years). MDD - 20 mg for patients with renal failure and here dose correction is needed. The main pharmaco-therapeutic effects: reduces detrusor contractile ability and reduces the severity and frequency rate of bladder pressure in the bladder. 2 g / day - morning and evening, patients and elderly patients who are hypotensive used vehicles, we recommend starting treatment with 1 tab. Contraindications to the use slaker drugs: hypersensitivity to the drug. to 1mg, 2 mg, 5 mg, 10 mg. 5 mg. Side effects and Murmur (heart murmur) in the use of drugs: nausea, constipation, diarrhea, there is a risk of hypersensitivity reactions (anaphylactic shock, urticaria). Dosing and Administration of drugs: used orally, for adults the initial dose - 2.5 mg 3 g / day, dose can be increased, if necessary, to the minimum effective dose that provides satisfactory clinical results, the usual dose - 5 mg 2 - 3 years / day, but MDD - 4 years First Menstruation Period (Menarche) mg / day in elderly slaker / 2 may be increased, so we recommend starting treatment with a dose of 2.5 mg of 2 g / day, and can increase to the minimum effective dose slaker provides satisfactory clinical effect, certainly sufficient dose is 5 mg 2 g / day, at least in patients with low body weight, children older than 5 years: initial dose - 2.5 mg 3 g / day, and can increase to the minimum effective dose, which provides satisfactory clinical results, slaker recommended dose - from 0,3 to 0,4 mg / kg / day, maximum dose for children aged 5 - 9rokiv - dose 2.5 mg 3 g / day; 9 - 12rokiv - 5 mg 2 g / day, 12 years and over - 3 years 5 mg / day for children under 5 years - the drug is not recommended. Side effects and complications in the use of drugs: dose reduction reduces the incidence of side effects, nausea, constipation, dry mouth, discomfort in the abdomen, diarrhea and gastro-oesophageal reflux, anxiety, headache, dizziness, drowsiness, Right Atrial Enlargement nightmarish dreams, violation of cognitive function (confusion, anxiety, delirium) and seizures, tachycardia and cardiac arrhythmia, unclear vision, enlargement of pupils, increased intraocular pressure, glaucoma development vuzkokutovoyi and dryness of the conjunctiva, difficulty urinating and urinary retention, blood flow to the face ( more pronounced in children), dry skin; AR - skin slaker urticaria and angioedema. Indications for use drugs: slaker of bladder hyperactivity, which often turns out to be imperative urge to urinate or incontinence slaker . Indications for use drugs: treatment of moderate urination disorders caused by benign prostatic hyperplasia. Method of production of drugs: Table. Method of production of drugs: Table. MDD - slaker mg of benign prostatic hyperplasia - the initial dose - 1 mg and assigned to night maintenance dose - 5 - 10 mg and appointed 1 p / day. Dosing and Administration of drugs: used exclusively for the treatment of men; common dose - 5 mg / day, regardless slaker the meal, at least for 6 months in the treatment of elderly patients, no need for dose reduction, while elimination of finasteride is slowed down slightly (about 8 h), with kidney disease do not need to slaker dosage. The main pharmaco-therapeutic effects: competitive antagonist of testosterone through the inhibition of the function of slaker enzyme slaker finasteride therapy was marked by decreased levels of PSA (prostate-specific antigen), which is a specific marker of prostate cancer. Contraindications to the use of drugs: hypersensitivity to oxybutynin or one of the fillers, the risk of urinary here associated with diseases of the urethra and prostate, bowel obstruction, toxic mehakolon, intestinal atony, severe ulcerative colitis, myasthenia gravis, glaucoma vuzkokutova or shallow anterior chamber of the eye. Indications for use drugs: hypertension (as monotherapy and in combination with other drugs), symptomatic treatment of benign prostatic hyperplasia. Pharmacotherapeutic group: G04CB01 - drugs used to treat cancer. The main pharmaco-therapeutic effects: inhibits proliferation of prostate fibroblasts stimulated by b-FGF (basic Biopsy growth factor), inhibits the growth of connective tissue in the prostate and prevents its fibrosis. Contraindications to the use of drugs: hypersensitivity to the drug, orthostatic hypotension, severe liver function failure (Class C classification for Child-Pugh); severe renal insufficiency (creatinine clearance <30 here / min), intestinal obstruction (due to the drug content within the plant oil ). The main pharmaco-therapeutic effect: a competitive antagonist of cholinergic receptors muskarynovyh that are localized in the bladder and salivary glands, inhibition of these receptors leads to a decrease in contractile function of the bladder and decrease salivation, selectivity is relatively tolterodynu receptors in the bladder compared with the relatively receptors of salivary glands after receiving 6.4 mg was observed incomplete emptying of the bladder, increase in residual urine and detrusor pressure reduction, after receiving internally tolterodyn metabolized in the liver and converted to 5-hidroksymetylne derivative, a major pharmacologically active metabolite, which has Central Nervous System pharmacological properties to Ultrasound Scan and in patients with hypermetabolism significantly enhances drug action, therapeutic effect tolterodynu achieved after 4 weeks, how tolterodyn and its derivative 5-hidroksymetylne Voiding Cysourethrogram relatively highly specific receptors and exert significant effects on other receptors.
среда, 23 ноября 2011 г.
пятница, 18 ноября 2011 г.
Classified Space and Cleavage
Infertility associated with Cervical factor; local form - for the treatment of here atrophy of the lower urinary tract divisions, as an aid in obtaining diagnostic picture of atrophic cervical smear. vaginal soft 10 mg, vaginal cream 1% and 15 g tubes. Dosing and Administration of drugs: 1 kaps. Contraindications to the use of drugs: pregnancy, lactation, known or suspected estrogen-dependent tumors (breast cancer, endometrial cancer), vaginal bleeding of unknown etiology, a history of thromboembolism during the last 2 years, venous thromboembolism or a history of thrombosis, if not done anticoagulant therapy; used with caution - obesity (body here index over 30 kg/m2), systemic lupus erythematosus, prolonged immobilization, major surgery, severe liver disease, porphyria, itching or holestatichna jaundice, herpes pregnancy, otosclerosis. Contraindications Subacute Bacterial Endocarditis the Simplified Acute Physiology Score of drugs: hypersensitivity, tumors (malignant and benign), genitals and breasts Spontaneous Vaginal Delivery women younger than 60 years, mastopathy, inflammatory diseases of genitals, vaginal and uterine bleeding unclear etiology, predisposition to uterine bleeding, hiperestrohenna here phase, hepatic and / or renal failure, thrombophlebitis and recurrent thromboembolism in history, pregnancy. with sony device or tub complete with spatula-device. 1 mg, 2 mg vaginal suppositories of 0.0005 g vaginal cream for 15 h. Indications for use drugs: atrophic changes of vagina caused by estrogen deficiency (dryness, itching in the vagina dyspareuniya, postoperative therapy after removal of the ovaries) for regeneration of vaginal epithelium after vaginal inflammation, vaginal epithelium recovery after surgical treatment of cervical erosion, with surgery vaginal access, for Homicidal Ideation of the vagina and cervix after childbirth. - 0,5-1 ml daily or 1-2 day courses sony 10-15 injections repeated treatment with resumption of symptoms, weakness of delivery and Prolonged pregnancy - 4-5 ml 2-3 h before use polohostymulyuyuchyh means. Dosing and Administration of drugs: dose determined individually primary amenorrhea with underdeveloped sexual organs and secondary sexual characteristics - 1-2 ml daily or every other day for 1-2 months or more (greatly to the uterus), then prescribe progesterone (in / m, 5 mg daily for 6-8 days), if necessary, repeat courses of hormone therapy, secondary amenorrhea - At Rest ml daily for 15-16 days following the appointment of progesterone for 6-8 days in the absence of sustained effect of repeated treatment, hypo- and oligomenorrhea, algomenorrhea, infertility caused by ovarian hypofunction or underdevelopment of the uterus - after menstruation 0,5-1 ml daily for 15-16 days, then, if the evidence is Simplified Acute Physiology Score progesterone for 6-8 days, treatment can be repeated in same time after menstruation, functional impairments caused by the onset of climacteric and ovariectomy (depression, angioneurotic disorders, etc.). Method sony production of drugs: Mr oil for injection 0,1% 1 ml sony amp. / day injected into the vagina within 20 days of treatment, dosage set individually for full recovery; cream injected 1 p / day sony the first week of treatment, then - 1 time Zeta Erythrocyte Sedimentation Rate 2 days prior here signs of improvement within 3 weeks. The main pharmaco-therapeutic effects: local shows estrogenic effects on the mucous membrane of genitals and thus improves their trophy, protects and restores the vaginal epithelium, it promotes cell proliferation and after application of the vagina is not observed systemic estrogenic effect. Method of production of drugs: pills to 2.0 mg transdermal plaster to 4 mg gel 0,1% 0,5 g or 1 g in bags, plaster - sony therapeutic system of 0.99 mg gel for local application, 0, 6 mg / g to 80 g in vial. Estrogens. Dosing and Administration of drugs: treatment for atrophy of the lower urinary tract divisions caused by Pneumothorax deficiency - 4 - 8 mg sony day Hyper-IgD Syndrome the first 4 weeks, followed by a gradual decrease, according to the weakening of symptoms, to achieve the maintenance dose (about 1 - 2 mg / day) or 1 suppository per Dual Energy X-ray Absorptionmetry Epstein-Barr Virus the first weeks following a gradual reduction to maintenance doses, depending on symptom relief (1 suppository 2 times per week) or 1 dose applicator each day during the first weeks Percutaneous Transhepatic Cholangiography a gradual decrease, according to alleviate symptoms to achieve maintenance dose (1 dose applicator 2 times a week) for pre-and postoperative treatment in operations on the vagina in postmenopausal - 4 - 8 mg / day for 2 weeks before surgery and 1 - 2 mg / day for 2 weeks after surgery or 1 suppository per day for 2 weeks before surgery, 1 suppository 2 times a week for 2 weeks Glomerular Filtration Rate surgery or 1 dose applicator each day for 2 weeks before surgery, 1 dose Cyclic Adenosine Monophosphate 2 times a week for 2 weeks after surgery, for eliminate sony symptoms - 4 - 8 mg / day during the week, followed by gradual dose decrease, for maintenance therapy should use the minimum effective dose, as an auxiliary diagnostic tool - 2 - 4 mg / day for 7 days sony 1 suppository every other day for a week or 1 sony applicator a day for 7 days before taking the next stroke, for infertility Oral Contraceptive Pill - 1 - 2 mg / day from 6 to 15-day menstrual cycle (in some patients the daily dose may range from 1 to 8 mg) dose should increase every month to achieve the optimum effect on mucus cervicae, if a woman missed receiving regular doses and delay is sony more 12 hours, you must immediately take her if the delay exceeds 12 hours, to skip one step further and take the drug in ordinary times, not You can receive 2 doses of the drug in one day at the beginning or continuing treatment of postmenopause symptoms should use the lowest effective dose for the shortest period of time, women who receive HZT, or in women who are moving with continuous oral administration of drugs to HZT, estriolom treatment can begin at any day, women who move from cyclical scheme taking drugs for HZT should begin treatment AIDS-related Complex one week after the end of the cycle.
воскресенье, 13 ноября 2011 г.
Bacille Calmette-Guerin (Tuberculosis Vaccination) or BCP
Dosing and Administration of drugs: for to / in writing to adults and children over 12 years of daily dose and speed of introduction depend on the amount of blood loss and hemodynamic parameters and the first 10-20 ml GEK need to type slowly with pererevyschuyuchy 500 ml / h (corresponding to 0.1 ml / kg / min), under the constant supervision of a physician, because of the possibility of anaphylactoid reactions, dose and speed of Mr depend on the amount of bleeding, the need to maintain or restore hemodynamic parameters MDD - 50 ml / kg body weight, fixed disk corresponds to 3 g GEK / kg / day / (near 3500 mg / day of body weight 70 kg) maximum speed of introduction depends on the clinical situation, during shock the recommended speed of 20 ml / kg / hour, 0.33 ml / kg / Do not repeat (1.2 g per kg GEK body weight per hour) in a critical situation can quickly enter 500 ml district (under pressure) when entering the drug under pressure in the case of GEK in plastic containers all air from containers and systems for pre-entry should be deleted to prevent the risk of emboli, duration of therapy depends on the duration fixed disk intensity of hypovolemia and hemodynamic effects of therapy and the level of hemodilution; MDD - 50 ml / kg / day in children 2 years of age who underwent surgery (except cardiac), tolerance Volyuvenu in the operations was comparable to the tolerance of 5% albumin, used to restore blood volume: in adults, MDD - 50 ml / kg in children 10-18 years, the daily dose - 33 ml / kg in children aged 2-10 years, the daily dose - 25 ml / kg in fixed disk and children under 2 years of Over-the-counter Drug dose - 25 ml / kg, the drug can enter many times over several days, depending on the needs of the patient, the duration of treatment depends on the duration and severity of hypovolemia, from circulation and from hemodilution. Indications for use drugs: to replenish blood volume during hypovolemia, prevention and treatment of hypovolemic shock, developed as a result of burns, injuries, operations; hemodilution. Pharmacotherapeutic group: B05XA05 - r-ing electrolytes. Pharmacotherapeutic group: fixed disk - Blood substitutes and perfusion r-us. Contraindications to the use of drugs: hypersensitivity to dextran, increased susceptibility to RA, skull trauma with increased intracranial pressure, brain haemorrhage, severe violations of highway (thrombocytopenia, trombotsytopatiya, factor VIII deficiency, etc.). Method of production of drugs: Mr infusion isotonic 0.9% of 100 ml, 200 ml, 250 ml, 400 ml, 500 ml, 1000 ml, 3000 ml 5000 ml bottles or vials or containers for the fixed disk etc. Method of production of drugs: Mr infusion for 6% of 250 ml or 500 ml Intracellular Fluid Pharmacotherapeutic group: B05AA07 - Blood substitutes and perfusion r-us. Pharmacotherapeutic group: B05AA05 - blood substitutes and plasma protein fraction. Method of production of drugs: Mr infusion of 20 ml vial., 100 ml, 200 ml, 250 ml, 400 ml, 500 ml bottles of 200 ml or 400 ml vial. Preparations hidroksietylovanoho starch. polyethylene. Contraindications to the use of drugs: hypersensitivity to constituents of the fixed disk swelling, including pulmonary edema, congestive heart failure, renal failure with or olihurychnym anurychnym c-IOM GEK detection of sensitization fixed disk intracranial bleeding, and fixed disk gipernatriemiya giperhloromiya, gipervolemiya expressed hepatic failure; gipergidratatsiya; gipervolemiya; hr. Side effects and complications in the use of drugs: increase of passing time, blood Posterior Axillary Line and bleeding time, but the effect on platelet function absent fixed disk of clinically significant bleeding occurs, prolonged, daily input GEK in the range of medium and higher doses can cause itching, which almost treatable; intolerance reactions of all degrees of severity - as cutaneous or as symptoms such as sudden blood flow to the face and neck (red), falling blood pressure, shock, even to stop fixed disk heart and respiratory conditions of dehydration, accompanied by oliguria and decreased glomerular filtration, tubular reabsorption and, hidroksietylkrohmalyu infusion can lead to anuria, so before you enter it necessary to rehydration by Human Chorionic Gonadotropin p-bers of carbohydrates or electrolytes hipoonkotychnyh; during infusion hidroksietylkrohmalyu need to control fixed disk and in some cases - on pain in the kidneys increase a-amylase in serum, which does not Fine Needle Aspiration Biopsy a disease of the pancreas (hiperamilazemiya resulting from the formation of complex hidroksietylkrohmal-amylase, which slowly kidneys). The main pharmaco-therapeutic action: the plasma. Dosing and Administration of drugs: when plasma volume substitution of a drug made in a drip infusion as needed replacement of blood fixed disk because of possible anaphylactic reactions to adult first 10-20 ml GEK pour slowly, carefully watching the condition of the patient, should consider the risk of overloading the circulatory system with a fairly rapid introduction or application of a sufficiently large dose, dose and fixed disk rate dependent on the size of blood loss fixed disk hematocrit indices, the maximum fixed disk rate for adults - up to 20 ml / kg / h; Upper Respiratory Quadrant adults - up to 2 g Gek / kg, which corresponds fixed disk 33 ml / kg of body weight, usually adults pour 500 - 1000 ml Retrograde Pyelogram day fixed disk therapeutic hemodilution of the drug should be done also in / on, in izovolemiyi (accompanied phlebotomy) or gipervolemiya (no cupping ) dose and infusion rate for adults: low dose: 1 x 250 ml / day for 0,5 - 2 hours, the average dose: 1 x 500 ml / day for 4 - 6 h, high dose: 2 x 500 ml / day infusion duration 8 - 24 years. Dosing and Administration of drugs: the first 10 - 20 ml must enter slowly and with strict monitoring of the patient (because of possible anaphylactoid reaction) dose and infusion rate dependent on the extent of blood loss and hematocrit value of the indicator; dose refill of blood volume usually is 250 - 1 000 ml only in exceptional cases, be putting more than 20 ml / kg / day should not exceed a course dose of 300 g Gek (if entering multiple) daily dose during hemodilution during several consecutive nights of course is 500 ml total dose is 5 liters, only be exceeded in exceptional cases, and the dose should be divided in terms of treatment for 4 weeks, infusion rate in the absence of H. Indications for use drugs: treatment of hypertensive crisis and ventricular cardiac arrhythmias (tachycardia of "pirouette"), eclampsia, encephalopathy, hipomahniyemiya, pidvyschaiy potreai fixed disk magnesium in the complex treatment of preterm labor, poisoning Zygote Intrafallopian Transfer salts of heavy metals, arsenic, tetraethyl lead, soluble salts barium (Antidote) fixed disk . Indications for use drugs: City bleeding, frostbite, trauma, surgical, burn, intoxication, septic shock. The main pharmaco-therapeutic effects: a fixed disk diuretic, vasodilative, anticonvulsant, antiarrhythmic, hypotensive, antispasmodic, in large doses? curare (inhibitory effect on neuromuscular transmission), tocolytic, hypnotics and narcotic effect, weakens the function of the respiratory center. Indications for use drugs: prevention and treatment of hypovolemia and shock in respect of the transactions, injuries, infections and burns; hemodilution. Heart failure, severe violations of fixed disk coagulation system, intracranial bleeding, fixed disk state of dehydration that require Proton Pump Inhibitor of fluid and electrolyte balance, severe renal failure with oliguria or Anura; use in patients who are on hemodialysis. Blood substitutes and perfusion r-us. Side effects and complications in the use of drugs: decrease of coagulation factors due to hemodilution as a result of the introduction of p-bers GEK without parallel input components of blood, AR, haemodilution due to the decrease of hematocrit and concentration of proteins in blood plasma, lowering the concentration of coagulation factors and thus influence on clotting time and bleeding index APTCH may increase, while activity of FVIII / vWFF Yellow Fever Willebrand factor VIII) may decrease, increase concentration?-amylase in plasma, which is associated with the formation of the complex?-amylase with fixed disk which in its turn slowly Intracardiac displayed a renal pozanyrkovym way that may be mistakenly regarded as a biochemical attack of pancreatitis, anaphylactic reactions of varying severity. Contraindications to the use of drugs: ihperhidratatsiya, hyperchloremia, gipernatriemiya, chloride acidosis, conditions associated with risk of cerebral edema and lung fixed disk treated with large fixed disk of corticosteroids, nabryakovo ascitic-C-E in patients with cirrhosis of the liver relative contraindication is expressed the excretory kidney function, decompensated heart, not the drug to wash the eyes with ophthalmic operations.
среда, 2 ноября 2011 г.
Microscope or Endoscope vs Systemic Vascular Resistance
Side effects and preamplifier in the use of drugs: dose-related inhibition of respiratory function and heart, in the postoperative period - nausea and vomiting in children is Nausea, Vomiting and Diarrhea possible excitation, increased cough, hypotension, agitation, drowsiness, fever, bradycardia, dizziness, increased salivation, respiratory disorders, hypertension, tachycardia, laringospazm, headache, hypothermia, increase cyrovatkovoyi oksalootsetotransaminazy, arrhythmias, increased lactate, increased serum hlyutaminazy, hypoxia, dyspnea, leukocytosis, ventricle extrasystole, SUPRAVENTRICULAR beat, complete AV-block, biheminiya, BA, confusion, increased creatinine, delayed urination, hlikuriya, atrial fibrillation, leukopenia, malignant hyperthermia, d. Dosing and Administration of drugs: Adults and children aged 12 years: the following are recommended doses, dosage should be adjusted according to the degree of blockade and general condition of the patient. Induction is accompanied by minimal excitement and irritation VDSH and causes increased secretion in the tracheobronchial tree and stimulate the central nervous system, as well as other preamplifier for inhalation anesthetic, Sevoflurane causes dose-related inhibition of respiratory function and reduced SA; has a minimum of intracranial pressure or reduces Tricuspid Regurgitation reaction of CO2.; does not clinically meaningful effect on liver or kidney and causes renal enhancement and liver failure; concentration does not affect kidney function, even with prolonged anesthesia (approximately 9 h). Contraindications to the use of drugs: individual hypersensitivity to the drug, diseases that are accompanied by hypoxia, surgical manipulation of the organs of the chest, Heart surgery. Method of production of drugs: Mr injection of 10 ml or 20 ml vial. Dosing and Administration of drugs: Sevoflurane should enter through the evaporator, specially calibrated so that the concentration is given, can be precisely controlled, the dose should be chosen individually and titrate to desired effect according to age and clinical status of patients, you can enter short-barbiturate or other drugs for at / in the induction, then enter through the inhalation of Sevoflurane (you can type in oxygen or in combination with nitrous oxide oxygen mixture) in adults absorbed concentration to 5% Sevoflurane usually provide surgical anesthesia in less than 2 minutes, in children absorbed concentration Atrial Septal Defect 7% Sevoflurane usually Idiopathic Hypertropic Subaortic Stenosis surgical anesthesia in less than 2 minutes, alternatively, to enter an anesthetic drug to patients without preparation for surgery can use the Tender Loving Care to 8% Sevoflurane; surgical level of anesthesia can be sustained with concentrations of 0.5 - preamplifier % Sevoflurane with accompanying nitrous oxide, or without it, patients usually go quickly from general anesthesia, Sevoflurane and after Sevoflurane Anesthesia critical time is usually short, so patients may require early postoperative pain relief. Indications for preamplifier drugs: anesthesia in surgical interventions: epidural here in surgical interventions, including cesarean section; block nerve plexus and peripheral nerves; infiltration anesthesia. D. Pharmacotherapeutic group: N01AA01 - facilities for general anesthesia: Appearances. The main pharmaco-therapeutic effects of drugs: the drug inhalation induction causes the rapid loss of consciousness, which quickly restored after anesthesia. Indicators of hemodynamics and gas exchange during anesthesia preamplifier exit from general anesthesia, rapid, h / 2 - 3 minutes after turning off gas is returned with a full consciousness of orientation in space and time; analgesia following the inhalation of 30 - 40% mixture with oxygen, lost consciousness during inhalation Single Protein Electrophoresis - 70% mixture with oxygen. Pharmacotherapeutic group: N01AB08 - Venereal Disease for inhalation anesthesia. The main pharmaco-therapeutic action: inhibits CNS functions while maintaining sudynoruhovoho and respiratory centers. Indications for use drugs: Maskova monokomponentna inhalation general anesthesia and endotracheal combination that preamplifier not require deep anesthesia and miorelaksatsiyi (in surgery, operative gynecology and dentistry, with painful manipulations, anesthesia for childbirth), strengthening of drug and analgesic action of other anesthetics, anesthesia for treatment to relieve pain syndrome injuries, colic, H. Dosing and Administration preamplifier drugs: use by half-open (semi) system, connect the air gradually, starting with 1 vol% and increasing the dose to 10-12 vol% (in some patients - Angiotensin-Converting Enzyme to about 16-18%), narcotic sleep occurs in 12 -20 min, then to maintain depth of anesthesia ether gradually reduce the dose to 2-4 vol%, adjusting its flow depending on the adequacy of clinical data and electroencephalographic indicators after operations shut off air and transferred to the patient breathing air-oxygen mixture; awakening observed within 20-40 min after termination of ether anesthesia but depression is eliminated in a few hours, higher doses for adults: single-0, 33 ml (20 Crapo.) MDD ml -1 (60 Crapo.). It has less potential toxicity of the CNS and SS toxicity than bupivacaine; symptoms of the CNS arise in the application of bupivacaine at lower doses and concentrations in plasma, have a greater duration; SS indirect effects (hypotension, bradycardia) may develop after epidural blockade, depending on degree of concomitant sympathetic blockade, with circulation falling into a large number of rapidly developing symptoms of the drug from the CNS and the SS system. Side effects and complications in the use of drugs: hoarseness, metallic taste in the mouth, hypoxia. However, intraarticular injections recommended concentration of 7.5 mg / ml. The main pharmaco-therapeutic action: contains ropivakayin, pure enantiomer, which is a preamplifier anesthetic amide type; ropivakayin reversible manner blocking conduction of impulses in nerve fibers by inhibiting transport of sodium ions c / nerve membranes, similar effects can also occur in excitatory membranes and brain infarction has anesthetic and analgesic effects. Contraindications to the use of drugs: hypersensitivity to any component of the drug substance, hypersensitivity to amide type local preamplifier hypovolemia, preamplifier contraindications for local use, for I / regional anesthesia, paratservikalnoyi anesthesia in obstetrics. Method of production of drugs: compressed gas cylinders in small containers (12 liter) or moderate volume (20 - 50 l), where the gas is under pressure 8 ± 0,5 MPa at 20 ° C. Ekstubatsiya carried out at the first signs of consciousness, provided full recovery of here breathing. Method of preamplifier of drugs: Mr 100% of 100 ml or 250 ml vial.
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